again IMO you are comparing apples to oranges
I just feel that the shortest path between sources is always the best and I always have concern that the more components the signal travels through only gives opportunity for coloration of the sound but that is just my opinion
My personal experience has been that by changing usb cables or the FO you get pretty much the same tonality. I don't notice any type of "different sound" or any coloration of the sound.
What I have experienced is more transparency and seeing way back into the depth of the soundstage and greater micro dynamics. The differences are subtle but the costs of the playing with the add-ons if one chooses to seem inexpenive compared to any other item in a top tier system.