Melanoma breakthrough

ack

VIP/Donor & WBF Founding Member
May 6, 2010
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Immunotherapy again

In what is being hailed as one of the biggest breakthroughs in melanoma treatment since the advent of immunotherapy, a new study has revealed that drug treatment before surgery is effective in preventing deadly spread of the disease.


The study, published today in the prestigious journal Nature Medicine, pooled data from six clinical trials where drug therapy was given before surgery, known as neoadjuvant therapy.


Researchers found that giving Stage III patients a short course of pre-operative targeted immunotherapy was effective, and the stronger a patient's response to that treatment in the first six to nine weeks, the greater the likelihood their disease would not recur after surgery. Remarkably, in the 75% of patients who responded well to dual immunotherapy given before surgery, only 3% saw their tumors return after surgery, suggesting that 97% will likely be cured.


"The neoadjuvant approach is a new way of dealing with melanoma and is a game changer for stage III patients with bulky disease that has spread to their lymph nodes," said Professor Georgina Long AO, Melanoma Institute Australia (MIA) Co-Medical Director and study senior author.


"We have flipped the 'surgery-then-drugs' rationale on its head. By using our arsenal of ground-breaking new treatments before surgical removal of the tumors, this approach is proving effective in stopping melanoma in its tracks and preventing its recurrence and spread to distant organs."


 

ack

VIP/Donor & WBF Founding Member
May 6, 2010
6,512
936
610
Boston, MA
Congrats. Enjoy life!
 

Steve Williams

Site Founder, Site Owner, Administrator
Melanoma can be a devastating disease. Even in pregnancy it can cross the placenta to affect the fetus
 
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