I assume there is nothing unique about running in these particular speakers. Just listening to music you like will do it. Symphonic music certainly gives speakers a workout. My speakers required 70 - 100 hours. No need to crank them at high volume.
It is also fun to give the different drivers a workout -- so, something bass heavy, then vocals and then something with a lot of high frequency content.
Speakers need some time to reach their best performance—more so than other components. IMHO, it takes around 1,000 hours for a speaker to fully break in since they are mechanical devices.
The most significant changes happen within the first 10 hours. From there, improvements gradually decrease but remain noticeable up to around 250 hours. Between 250 and 1,000 hours, the changes become more subtle. During this period, speakers tend to sound more relaxed and detailed while also becoming smoother and lively.
On the downside, bass control may weaken, and there can be some fluctuations in the overall sound like sounding great one day and terrible the day after.
You can drastically shorten the break-in time by placing a thick wool blanket over the speakers, turning up the volume, and letting the CD play continuously, even when you're not at home. Surrounds and diaphragms need some time to become flexible.
When I am not at home for say a week, they do need a run in.
Something with bass, maybe Yello playlist from Qobuz for a few hours at a volume above my usual setting, when I am not at home.
This really opens them up, improving literally all things.
Not a subtle difference.
My PAP Quintets with the Voxativ 1.6 needed 200-300+ hours before it really started to shine. Sounded bad for the first month, had a pit in my stomach thinking I made a mistake. Then one day, it hit me WOW! it's been 4 years and I'm still smitten with them.
I'm also a proponent of cranking the volume and letting them play for 30-45 minutes every few months. I generally listen with peaks under 75db. I'll crank it to 80db+ average and leave the room while I do other things in the house and come back.