I don't recall the exact context but it was said that gross diffefrences blot out bias. You might imagine Tim I remain skeptical.
I think there's some truth in that. They blot it out or they clearly define it. If you love vinyl, through low powered SET into horns, you're not likely to suddenly decide you like hi-res digital files through active monitors and subs better, just because your eyes are closed. And if you're listening blind just to see if you can hear the difference, not to choose a preference, well, of course, the more subtle the difference, the more useful the blind listening. If you can't identify a difference between Klipschorns and Magicos with your eyes closed, we have a whole other set of issues.
Tim