I guess I fall in the category of "people get off on having one of a kind piece that just a handful of people in the whole world can have" as I own:
Galibier Stelvio Turntable (Thom Mackris)
2 Talea tonearms (Joel Durand)
Experience Music phono and line stages (Jeffrey Jackson)
Daedalus Ulysses speakers (Lou Hinkley)
This has been a gradual evolution for me. Prior to purchasing my Stelvio three years ago, I owned 'brand name' high end gear and honestly had a bit of undeducated contempt for smaller manufacturers. Two things opened my mind to the path I've subsequently embraced...a) I actually auditioned the equipment and b) I had an incredibly unpleasant repair experience with a 'name brand' piece of equipment.
"But does it really make sense to get an almost one of a kind piece of audio gear?"
My answer would be a firm MAYBE
Many audiophiles prefer to work with a dealer and develop a level of comfort having a 'name brand', especially if you like the equipment's sound. In my experience, most folks are happy with this arrangement. However...if you want to push the envelope and/or you are not satisfied with the sound of 'name brands', smaller manufacturers are the way to go. Additional benefits include participating in product development, personal service from the designer and getting a piece of equipment tailored to your taste and system. As an example, Thom Mackris delivered and set up my turntable which was terrific because he knows what appropropirate set up sounds like! I was able to get my phono stage with separate step ups for mono and stereo (hand wound by Dave Slagle) and mercury rectification in the power supply. Jeffrey will deliver and tune my line (and phono) stage next month.
Are there negatives to going this route...absolutely. You have to do your research about the equipment and more importantly the people behind the equipment. Patience is a virtue...many small manufacturers also have day jobs. That said, my experience has been superlative and has brought my system to a higher level of enjoyment and I've met some great people along the journey.