The on-off debate is VERY hard to answer competently to say the least.
Tubes were designed to be abused like hell and they withstand anything and everything. After all they are not a watch but just a piece of hard metal in the vacuum. Nothing complicated.
The only way the tube may die is when it has air inside which happens when glass has a crack. Or if excess heater current is used for extended period of time. Or if excess anode current is drawn for extended period of time. Theoretically on-off should not affect tube life by much. Nobody, including the manufacturers - knows how long the tube will live. The so called tube life expectancy is BY NO MEANS any indicator how long a tube will live. This number is simply an agreement between manufacturer and ordering party about what life expectancy will be covered by a warranty. So it is in the interest of manufacturer to put the lowest number humanly possible, that they can get away with. and it is when ALL and every limiting parameter is reached all at the same time. Like max voltage, max current, max capacitor, max external temp, max heaters, and 10% excess on top. In the contract between say Raytheon, the maker of missiles and RCA they would say: the tube must live minimum 2000 hours - and that figure goes to datasheet. In my personal experience a normally used tube lives 20 years no matter if you switch them on-off or not. When I started the business, most of my tubes used to cost 3-5 dollars so nobody really cared how long they will live - 10 or 20 years. Now some rare tubes cost in excess of 500 dollars a piece so we do care.
I would leave a take away advice - switch off for holidays, vacations, and the night. But not when you go to get something from the kitchen. Keep it sane and DONT WORRY too much. Anyway - 99% tubes will die due to an event unrelated to normal use - they get broken, dropped, mis-inserted, they have internal defects, etc. In our DACS we use the tubes up to 20% of full power ratings so they are treated SUPER LIGHTLY. Unlike in a power amps where every tube is used 101% of the limits. In these conditions most tubes live 5-10 years. I have a customer whose monoblocks (old VTL) have russian "C" 6550 's and they have been running 35 years and didnt drift even 5%. I also have PSVANE 101d's that live a week or two. Again - dont worry and enjoy!
P.S. there is no such thing as standby for the tube circuit. The tubes must either be in nominal parameters or fully off. The tubes CAN NOT be in "half parameters". Whoever says differently - is lying.