Newton,
You have a very nice looking room and budget. As helpful as everyone here is, I think the best advice I could give you is to add a little bit to the budget for traveling to dealers or owners' houses who have the speakers you are considering.
I just hosted a friend who flew in to Houston from New Orleans. He was considering YG, Rockport and MBL. I actually filmed much of the demo so I'll put a link below.
I think my friend will confirm that the smartest thing he did was flying over to listen. He was totally convinced he was getting YG Sonia 2.2 a month ago, but changed his mind after direct demos. It wasn't that the YG disappointed. He actually called it "audio mecca", but he was looking for a change and there are so many other factors like personal taste that we on a message board can't help you with.
It's a lot of money, so it's important that you are totally happy. Try to listen before you buy if at all possible.
If I were to just give my two cents based on looking at your room and limited info, I think you're on the right track with getting a sealed cabinet like YG to mate with your subs if that's something currently bothering you.
However, without being in your room to know for sure, my inclination is to suggest you consider something else as well. You basically have a room without boundaries so pressurizing that space will be tough regardless of what speaker you choose.
You may want to consider MBL because they somewhat use the room to your advantage and typically sound more spacious in cavernous size rooms like yours. It would take a little finesse in setting up and there are no guarantees, but I would recommend considering it.
One thing to note...it looks like your room doubles as an entertaining and group hangout. Thus, the MBLs would provide better off axis listening to a larger range of people..even if they are standing right to the side of it.
Also, your room is an ideal candidate for a line source. They lose half as much volume as you double the distance so it will fill your space easier. It will also fill it better because they are typically tall and have a more grandiose vertical soundstage which seems ideal for your room. You also have less floor/ceiling reflections with a line source.
For my personal tastes, a line source is definitely the way to go in that room. The Wisdom Audio LS4 or the Alsyvox Botticelli would be on my shortlist. If you haven't heard a line source like that in your room or similar, I would recommend at least giving it a demo. You may fall in love with it like I have over the years.
From an aesthetic perspective, the Dynaudio Evidence Temptation would give you a similar profile to the KEF blades, but much higher performance I believe. A first order crossover in a speaker of that quality can be magic if setup right.
https://www.youtube.com/playlist?list=PLPt7qoWWa8yhhBRvE-rUuGhA6vbq-KsBo