Perhaps one other twist is where the speaker designer has actually created the separate passive and active units in a 4-tower configuration...Tidal, Gryphon, Genesis, Marten Coltrane, Evolution and (in a way) Wilson XLF + Thor. This way, the deep bass modules are separate, but designed as an integrated whole with the main speaker. I have even heard the CLX + Descent subs with the settings specifically for the link to CLX, and it was impressive.
Thus, one gets the benefit of active bass plus passive (smaller Genesis, Gryphons, VS) where one designer ensured everything is a fully integrated design (power, crossover, impedance matching, etc)...but also with the benefit of separate bass modules for optimal room placement (and also to avoid vibrational issues).