If I am to choose a low power tube for an audio amplifier, among the classic tube variants, I would definitely go for 45. I am not experienced at all with 46, so I can't comment on this. As soon as Bill declares his preference, I cannot comment on this,logically it has many pros.
I had played with 45 12-13 years ago. It was my favorite. My favorite piece among audio tubes, before migrating to the transmitters' sound. Since I crossed the forbidden territories of 801 and then vt-25, I never came back. My last step was (and still is) RS241, a truly amazing tube. And of course the British variant of 834, named STC 4304, along with the UFO 316a.
In my opinion, these tubes are the best sounding valves ever made. They have somewhat higher distortion but their sound is so dynamic, glossy and thrilling that you forget everything else. And of course combined with mercury vapor rectifiers and tube rectified filaments, with Tungar bulbs.
I am now designing my new loudspeakers from scratch, field coiled of course, powered with mercury vapor tubes. I will report as soon as I have reached a good point of progress.