This Corona Virus Mania is Just Too Much, We All Need to Chill!

[Hi-FiGuy]

I have witnessed a couple of outbreaks firsthand in the 90’s too

must have been a mutation

 

[andromedaaudio]

Here is another virus expert , with a kind of differnt opinion.
Just a pandemic as any other , a bit worse , but it lll all be over in a few weeks .

 

[PeterA]

 

[twitch]

Hilarious. Very funny and very topical. I will share it with my children to teach them a little bit about punctuation and how it can alter meaning.

awe, you guys aint no fun......

 

[jeff1225]

Amazing videos are showing up on YouTube splicing together old clips of various politicians, news commentators and celebrity doctors downplaying the seriousness of Covid-19. Here's Dr. Drew's apology:

https://time.com/5816604/dr-drew-apologizes-coronavirus/

 

[Bobvin]

Here is another virus expert , with a kind of differnt opinion.
Just a pandemic as any other , a bit worse , but it lll all be over in a few weeks .

Whats this? Some kind of pandemic denier? Don’t you know the science is settled? 97% of scientist who don’t study pandemics agree on...

Oh, sorry, forgot where I was! (Don’t ban me or give me too many demerits.)

 

[MPS]

Interesting site, you can "play around" with database to create graphs of your own.

https://covidly.com/graph

 

[Al M.]

How did coronavirus break out? Theories abound as researchers race to solve genetic detective story

 

[NorthStar]

Shit happens.

 

[Gregadd]

We should direct our resources to containment cure and vaccine.

 

[Folsom]

How did coronavirus break out? Theories abound as researchers race to solve genetic detective story

Reads more like lab workers protecting lab workers than anything.

But honestly it doesn't matter too much right now, Greg is right that we have more pressing priorities.

 

[marty]

I know this may be a bit technical, but it's really a good insight into the mechanism by which the virus causes acute respiratory distress syndrome which is what kills infected patients. It's all about a hyperinflammatory state that goes by the name of cytokine storm syndrome.

Why the immune system fails to mount an adaptive immune response to a Covid ?19 infection

It seems these guys figured it out. Makes sense.
Looks like this story is similar to the side effects of CAR T cell therapy for pediatric acute lymphocytic leukemia that were due to cytokine release syndrome, thus warranting anti-TNF treatment. This is good news for potential therapy. Unfortunately, I imagine there will be rapid off-label use of drugs such as tocilizumab (IL-6 receptor blockade) and anti-TNF drugs such as Humira well before the ongoing studies can be completed.

 

[NorthStar]

We should direct our resources to containment cure and vaccine.

We are Greg; should be ready to test on humans Spring 2021 @ the earliest.
That's good news yes?

* Before releasing a bug in the open we should always have a bug zapper developed already.
Get the bug zapper first, then you can release the little nasty sunnabaggun bug.

 

[NorthStar]

I know this may be a bit technical, but it's really a good insight into the mechanism by which the virus causes acute respiratory distress syndrome which is what kills infected patients. It's all about a hyperinflammatory state that goes by the name of cytokine storm syndrome.

Why the immune system fails to mount an adaptive immune response to a Covid ?19 infection

It seems these guys figured it out. Makes sense.
Looks like this story is similar to the side effects of CAR T cell therapy for pediatric acute lymphocytic leukemia that were due to cytokine release syndrome, thus warranting anti-TNF treatment. This is good news for potential therapy. Unfortunately, I imagine there will be rapid off-label use of drugs such as tocilizumab (IL-6 receptor blockade) and anti-TNF drugs such as Humira well before the ongoing studies can be completed.

 

[bonzo75]

I know this may be a bit technical, but it's really a good insight into the mechanism by which the virus causes acute respiratory distress syndrome which is what kills infected patients. It's all about a hyperinflammatory state that goes by the name of cytokine storm syndrome.

Why the immune system fails to mount an adaptive immune response to a Covid ?19 infection

It seems these guys figured it out. Makes sense.
Looks like this story is similar to the side effects of CAR T cell therapy for pediatric acute lymphocytic leukemia that were due to cytokine release syndrome, thus warranting anti-TNF treatment. This is good news for potential therapy. Unfortunately, I imagine there will be rapid off-label use of drugs such as tocilizumab (IL-6 receptor blockade) and anti-TNF drugs such as Humira well before the ongoing studies can be completed.

Yes, they found that they can use a drug to calm the immune system after it defeats the virus to stop it from further attacking your organs

 

[dminches]

I know this may be a bit technical, but it's really a good insight into the mechanism by which the virus causes acute respiratory distress syndrome which is what kills infected patients. It's all about a hyperinflammatory state that goes by the name of cytokine storm syndrome.

Why the immune system fails to mount an adaptive immune response to a Covid ?19 infection

It seems these guys figured it out. Makes sense.
Looks like this story is similar to the side effects of CAR T cell therapy for pediatric acute lymphocytic leukemia that were due to cytokine release syndrome, thus warranting anti-TNF treatment. This is good news for potential therapy. Unfortunately, I imagine there will be rapid off-label use of drugs such as tocilizumab (IL-6 receptor blockade) and anti-TNF drugs such as Humira well before the ongoing studies can be completed.

Marty, am I correct in saying that having been exposed to other viruses in the past is good if you are re-exposed to those viruses but not good if you are exposed to a new virus since the t-cells are not as effective?

 

[Al M.]

Reads more like lab workers protecting lab workers than anything.

Or not wanting to believe that scientist colleagues could be that sloppy. At least some scientists admit that the lab accident hypothesis has credence.

But honestly it doesn't matter too much right now, Greg is right that we have more pressing priorities.

Agreed, but we still have to prevent the next outbreak, so it's important to get to the bottom of what happened. For example if it was farmers who use bat feces for fertilizing, that's needs to be addressed. But we may never know.

 

[bonzo75]

Marty, am I correct in saying that having been exposed to other viruses in the past is good if you are re-exposed to those viruses but not good if you are exposed to a new virus since the t-cells are not as effective?

Cytokine is where the immune system stays in an energized state after defeating the virus, and continues to attack your organs, instead of going back to normal

 

[ddk]

Here is another virus expert , with a kind of differnt opinion.
Just a pandemic as any other , a bit worse , but it lll all be over in a few weeks .

I like this guy and what he says makes sense in it's own right.

david

 

[Al M.]

I like this guy and what he says makes sense in it's own right.

david

No it doesn't. Speaking between 6 and 7 minutes he concludes that 10,000 people would die (it seems he means even without social distancing, but this is not quite clear to me). Yet this is nonsense. We are already above 10,000 deaths (with the number probably being underreported), and this will increase several fold in the next few weeks.

He says he is not being paid by the government and thus can do actual science. This is quite an arrogant thing to say, shockingly so for a scientist. Are all the other scientists shills for the government? That sounds like a conspiracy theory to me.