R&D includes all costs. My companies that I have worked for have never spent even $10b in total on R&D. Yes, I know Oncology is more expensive, but still no single drug costs over $1B.If you want to includes all unrelated costs, then why not the Janitorial/finance/admin costs too?LoL
Perhaps some of these companies need to be more judicious in their spending. The direct cost per drug may not be the issue...
YOU DO include those costs because they ARE related to what the company must do to run itself and stay in business.