My son in law told me that the FDA is fast tracking these drugs
as far as renal failure I am no expert so what I say is not gospel. From what I am reading the renal failure is caused by micro thromboses in the kidneys rather than from only ACE-2 but in all likelihood it remains as yet poorly understood
Bottom line is simple. It isn't the virus that is going to kill you but rather the comorbidities such as ARDS and organ failure (heart, lungs, kidneys) as a result of the cytokine storm
You're right, comorbidities is the biggest issue. But not everyone has a cytokine storm, a large number of patients are having straight up failure without that auto-immune level response - or even after they get off of the machines and appear ok breathing wise. Regardless we have to work on the things we can influence efficiently.
BTW ACE-2 is the good enzyme that prevent run away ACE (which has it's own role, to make sure blood pressure doesn't drop 0 for instance). You'll call me crazy but if I could sneak in little packets of olive oil for jaioviera's friend to dip his food in, I would. You can't heal anything by reducing ACE, but it helps create the conditions so that it's possible.