They are blowing because they are not made right or to spec, if you have to start raising the amperage on a fuse to go way above what the unit is rated for that should scare the hell out of you if you have a power surge and 2nd tells you how poorly these homemade fuses are made. It is irresponsible of these sellers and is BS that they blow is due to the cause of high tolerance, it is the opposite, but they are money to be made. Not a bad side job at $2,000 a pop.
Anything you change in a decent system will give you a slightly different sound, all of these types of tweaks cannot ever lose because they will all change the sound be it a better ceramic fuse vs. glass, or those who peddle $2,000 fuses, and all in between.
All cables change the sound no matter the cost from a $300.00 to $30,000 power cords do also, but your room should be your number 1 concern so spend the same $2,000 on your room, that will be money well spent, but if you are so well off that you can toss $2,000 at fuses, well more power to you go for it. But that money can be better used elsewhere in your system.
Then send some money to the Ukraine Charity while you spending $2,000 on fuses, that same amount of money would help real people who are in need, and that be money better spent than on a fuse that is less reliable than a 15 cent fuse. In my lifetime besides failing once in a blue moon or blowing from a power surge I've had them in my gear for years and years and never an issue like some are experiencing.