Again, Placebo is a wrong analogy. Placebo in medicine happens because there is no way for me to distinguish the difference between a placebo pill and a real pill at the point of intake - I have to trust the doctor's word. They both look the same and taste the same. However, it is possible for me to distinguish differences in sound at the point of intake. A better analogy is, if the real pill was sweet, and the placebo one was savoury, then you are alleging that the Entreq guys thing sweet is savoury or vice versa, based on imagination.
Also, placebo is possible if one auditions something once or twice. Not when someone auditions it twenty times in different scenarios. I don't own Entreq, haven't demoed it at home, and have no plans to buy a grounding box in the near future because I have other expenses on hifi planned (better speakers, turntables, cartridges, etc which should keep me bankrupt for the next decade). However, I have zero reason to believe it works, because so many people can't imagine differences over 2 years, especially where some reported that with a particular setting they couldn't, and with another they could. Whether the differences are always positive, I do not know. Just like cables. Cables do sound different, whether they are worth it, and whether differences are always positive, is another discussion